연구실소개
학력
M.D., Ph.D. Seoul National University College of Medicine
주요관심 연구분야
- Molecular Pathology
- The Target validation of Anti-cancer Proteins by clinicopathological analysis
- Phenomics: large-scale phenotype identification of genetically engineered mouse
- preclinical assessment of therapeutic antibody
대표논문자료
- Choi YL, Oh E, Park S, Kim Y, Park YH, Song K, Cho EY, Hong YC, Choi JS, Lee JE, Kim JH, Nam SJ, Im YH, Yang JH, Shin YK. Triple-negative, Basal-like, and Quintuple-negative Breast Cancers: Better Prediction Model for Survival. BMC CANCER 23 (2010.09)
- Kwon MJ, Kim SS, Choi YL, Jung HS, Balch C, Kim SH, Song YS, Marquez VE, Nephew KP, Shin YK. Derepression of CLDN3 and CLDN4 during Ovarian Tumorigenesis is Associated with Loss of Repressive Histone Modifications. CARCINOGENESIS 31, pp. 974-983 (2010.06)
- Kundu JK, Hwang DM, Lee JC, Chang EJ, Shin YK, Fujii H, Sun B, Surh YJ, Inhibitory effects of oligonol on phorbol ester-induced tumor promotion and COX-2 expression in mouse skin: NF-kappa B and C/EBP as potential targets. CANCER LETTERS 273, pp. 86-97, (2009.01)
- Kim KH, Choi JS, Kim JM, Choi YL, Shin YK, Lee HC, Seong IO, Kim BK, Chae SW, Kim SH, Enhanced CD24 expression in endometrial carcinoma and its expression pattern in normal and hyperplastic endometrium. HISTOLOGY AND HISTOPATHOLOGY 24(3), pp. 309-316, (2009.03)
- Kim HJ, Kim JH, Shin YK, Lee SI, Ahn KM, A novel mutation in the linker domain of the signal transducer and activator of transcription 3 gene, p.Lys531Glu, in hyper-IgE syndrome. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 123(4), pp. 956-958, (2009.04)
- Na TY, Shin YK, Roh KJ, Kang SA, Hong I, Oh SJ, Seong JK, Park CK, Choi YL, Lee MO, Liver X Receptor Mediates Hepatitis B Virus X Protein-Induced Lipogenesis in Hepatitis B Virus-Associated Hepatocellular Carcinoma. HEPATOLOGY 49(4), pp. 1122-1131, (2009.04)
- Yin HQ, Kim YC, Chung YS, Shin YK, Lee BH, Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes. TOXICOLOGY AND APPLIED PHARMACOLOGY 236, pp. 124-130, (2009.04)
- Kwon MJ, Oh E, Lee S, Roh MR, Kim SE, Lee Y, Choi YL, In YH, Park T, Koh SS, Shin YK Identification of Novel Reference Genes Using Multiplatform Expression Data and Their Validation for Quantitative Gene Expression Analysis. PLoS One 7;4(7):e6162. (2009.07)
- Lee MH, Choi BY, Kundu JK, Shin, YK, NA HK, Surh YJ, Resveratrol Suppresses Growth of Human Ovarian Cancer Cells in Culture and in a Murine Xenograft Model: Eukaryotic Elongation Factor 1A2 as a Potential Target. BREAST CANCER RESEARCH AND TREATMENT 69(18), pp. 7449-7458, (2009.09)
- Choi, H. J., Shin, Y. K., Lee, H. J., Kee, J. Y., Shin, D. W., Lee, E. Y., Lee, Y. J., Lee, E. B., Song, Y. W., The clinical significance of serum N-terminal pro-brain natriuretic peptide in systemic sclerosis patients. Clinical Rheumatology 27, pp. 437-442 (2008.04)
- Yoo Y-G, Na T-Y, Seo HW, Seong JK, Park CK, Shin YK, Lee M-O., Hepatitis B virus X protein induces the expression of MTA1 and HDAC1, which enhances hypoxia signaling in hepatocellular carcinoma cells. Oncogene 27, pp. 3405-3413 (2008.05)
- Yang YD, Cho H, Koo JY, Tak MH, Cho Y, Shim W-S, Park SP, Lee J, Lee B, Kim B-M, Raouf R, Shin YK, Uhtaek Oh., TMEM16A confers receptor-activated calcium-dependent chloride conductance, Nature 455, pp. 1210-1215 (2008.10)
- Kim SH, Lee S-H, Choi Y-L, Wang L-H, Park CK, Shin YK., Extensive alteration in the expression profiles of TGFB pathway signaling components and TP53 is observed along the gastric dysplasia-carcinoma sequence., Histology and Histopathology 23, pp. 1439-1452 (2008.12)
- Wang L-H, Kim S-H, Lee JH, Choi Y-L, Kim YC, Park TS, Hong Y-C, Wu C-F, Shin YK, Inactivation of SMAD4 Tumor Suppressor Gene During Gastric Carcinoma Progression. Clinical Cancer Research 13(1), pp. 102-110 (2007.01)
- Choi Y-L, Lee S-H, Kwon G-Y, Park C-K, Han J-J, Choi J-S, Choi H-Y, Kim S-H, Kim S-H, Shin YK, Overexpression of CD24: Association with Invasiveness in Urothelial Carcinoma of Bladder., Archives of Pathology & Laboratory Medicine 131(2), pp. 275-281 (2007.02)
- Lee JH, Kim S-H, Wang L-H, Choi Y-L, Kim YC, Kim JH, Park TS, Hong Y-C, Shin YK, Clinical significance of CD99 downregulation in gastric adenocarcinoma., Clinical Cancer Research 13(9), pp. 2584-2591 (2007.05)
- Choi Y-L, Kim J, Kwon MJ, Choi J-S, Bae D-S, Kim T-J, Koh SS, In Y-H, Park YW, Kim SH, Ahn G, Shin YK, Expression profile of Tight Junction Protein Claudin 3 and claudin 4 in Ovarian Serous Adenocarcinoma with prognostic correlation. Histology and Histopathology 22(11), pp. 1185-1195 (2007.11)
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