학력
서울대 약학대학 학사
서울대 약학대학 석사
미국웨인주립대학 의과대학 박사
주요관심 연구분야
- 지방조직 줄기세포 분화기전 연구
- 유전자조작 마우스를 활용한 대사질환 신규 표적 발굴
- 지방조직유래 생체지질 및 엑소좀 생리 활성 연구
- 비만, 당뇨 및 노화성 대사질환 치료제 개발을 위한 지방조직 리모델링 유도물질 탐색
대표논문자료
[대표 논문 10편]
- Cho YK, Son Y, Kim SN, Song HY, Saha A, Ahn SY, Kim MS, Park JH, Jung YS, Granneman JG, Lee YH* MicroRNA-10a regulates macrophage polarization and promotes therapeutic adipose tissue remodeling. Molecular Metabolism (2019, in press)
- Song HY, Kim SN, Saha A, Ahn SY, Akindehin S, Son Y, Cho YK, Kim MS, Park JH, Jung YS, Lee YH* Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction. Aging and Disease (2019, in press)
- Kim, S.N., Akindehin, S., Kwon, H.J., Son, Y.H., Saha, A., Jung, Y.S., Seong, J.K., Lim, K.M., Sung, J.H., Maddipati, K.R., Lee YH* Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice. Scientific reports 8, 8856 (2018)
- Burl RB, Ramseyer VD, Rondini EA, Pique-Regi, Lee YH, Granneman JG Deconstructing adipogenesis induced by ß3-adrenergic receptor activation with single cell expression profiling Cell Metabolism, 28, 300-309.e304. (2018)
- Kim, S.N., Akindehin, S., Kwon, H.J., Son, Y.H., Saha, A., Jung, Y.S., Seong, J.K., Lim, K.M., Sung, J.H., Maddipati, K.R., Lee YH* Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice. Scientific reports 8, 8856 (2018).
- Kim SN, Kwon HJ, Im SW, Son YH, Akindehin S, Jung YS, Lee SJ, Rhyu IJ, K IY, Seong JK, Lee HC, Lee J, Granneman JG, Lee YH* (2017) Connexin 43 is required for the maintenance of mitochondrial integrity in brown adipose tissue. Scientific reports 7(1):7159 (2017).
- Kwon HJ, Kim SN, Kim YA, and Lee YH*: The contribution of arachidonate15-lipoxygenase in tissue macrophages to adipose tissue remodeling. Cell Death & Disease 7(6):e2285 (2016)
- Lee YH, Petkova AP, Konkar A, Granneman JG: Cellular origins of cold-induced brown adipocytes in adult mice. FASEB Journal 29(1): 286-99 (2015)
- Lee YH, Petkova AP, Granneman JG: Identification of an adipogenic niche for adipose tissue remodeling and restoration. Cell Metabolism 18 (3): 355-367 (2013)
- Lee YH, Petkova AP, Mottillo EP, Granneman JG: In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high fat feeding. Cell Metabolism 15 (4): 480-491 (2012).
