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서울대학교 서울대학교 약학대학

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교수진

박성규 교수

전공미생물 및 면역학
주소21-306
연락처880-8180 / 7864
이메일riceo2@snu.ac.kr
학력

Ph.D. Seoul National University(2003)

주요관심 연구분야
  • 바이러스 감염성 면역질환 연구
  • 감염에 의한 T세포 활성화 분자기전 연구
  • 항바이러스제 개발 연구
대표논문자료
  1. Jung-Ah Kang, Songwon Kim, Minji Park, Hyun-Jin Park, Jeong-hyun Kim, Sanghyeok Park, Jeong-Ryul Hwang, Yong-Chul Kim, Yoon Jun Kim, Yuri Cho,* & Mi Sun Jin,* and Sung-Gyoo Park*. Compound AC inhibits Hepatitis B Virus secretion by blocking capsid assembly. Nature Communications. 10(1):2184. 2019 May. *Co-correspondence
  2. Eunkyong Ko, Jong‐Seo Kim, Soomi Ju, Hyun‐Wook Seo, Yeonji Chang, Jung‐Ah Kang, Sung‐Gyoo Park*, and Guhung Jung*. 2018. Oxidatively modified PDIA3 promotes DKC1‐mediated malignancy and survival of hepatocellular carcinoma cells. Hepatology, 68(5):1851-1864. 2018 Nov. *Co-correspondence
  3. Cho-Rong Lee, Yewon Kwak, Taewoo Yang, Jung Hyun Han, Sang-Heon Park, Michael B. Ye, Wongeun Lee, Kyu-Young Sim, Jung-Ah Kang, Yong-Chul Kim, Sarkis K. Mazmanian, and Sung-Gyoo Park. 2016. Myeloid derived suppressor cells are controlled by regulatory T cells via TGF-bduring murine colitis. Cell Reports, 17(12):3219-3232. 2016 Dec
  4. Jieun Seo, Jung-Ah Kang, Dong In Suh, Eun-Byeol Park, Cho-Rong Lee, Sun Ah Choi, Soo Yeon Kim, Yeji Kim, Sang-Heon Park, Soon-Hak Kwon, June Dong Park, Byung Chan Lim, Dong Hun Lee, Suk-Jo Kang, Murim Choi*, Sung-Gyoo Park*, Jong-Hee Chae*. 2016. Tofacitinib relieves symptoms in STING-associated vasculopathy with onset in infancy caused by two de novovariants in TMEM173. Journal of Allergy and Clinical Immunology, 139(4):1396-1399.*Co-correspondence
  5. Jung-Ah Kang, Sang-Heon Park, Sang Phil Jeong, Min-Hee Han, Cho-Rong Lee, Kwang-Min Lee, Namhee Kim, Mi-Ryoung Song, Murim Choi, Michael B. Ye, Guhung Jung, Won-Woo Lee, Soo Hyun Eom, Chul-Seung Park, and Sung-Gyoo Park. 2016. Epigenetic regulation of Kcna3-encoding Kv1.3 potassium channel by cereblon contributes to regulation of CD4+ T cell activation. Proceedings of the National Academy of Sciences USA, 113(31):8771-8776. 2016 Aug
  6. Sangmoon Lee, Jin Soo Moon, Cho-Rong Lee, Hye-Eun Kim, Sun-Mi Baek, Solha Hwang, Gyeong Hoon Kang, Jeong Kee Seo, Choong Ho Shin, Hyoung Jin Kang, Jae Sung Ko*, Sung Gyoo Park*, Murim Choi*. 2015. Abatacept alleviates severe autoimmune symptoms in a patient carrying a de novo variant in CTLA-4. Journal of Allergy and Clinical Immunology, 137(1): 327-330. *Co-correspondence
  7. Ramkumar Mathur, Hyunju Oh, Dekai Zhang, Sung-Gyoo Park, Jin Seo, Alicia Koblansky, Matthew S. Hayden, Sankar Ghosh. 2012. A Mouse Model of SalmonellaTyphi Infection. Cell, 151(3): 590-602. Oct 26, 2012
  8. Sung-Gyoo Park, Meixiao Long, Ramkumar Mathur, Matthew S. Haden, Namiko Hosh, Liming Hao, Sankar Ghosh. 2010. Suppression of TCRgd T-cells by T-regulatory cells helps maintain intestinal homeostasis. Immunity, 33(5): 791-803. Nov 24, 2010
  9. Meixiao Long, Sung-Gyoo Park, Ian Strickland, Matthew S. Hayden and Sankar Ghosh. 2009. Nuclear Factor-kB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor. Immunity,31(6): 921-931. Dec 18, 2009
  10. Sung-Gyoo Park, Jan Schulze-Luehrman, Matthew S. Hayden, Naoko Hashimoto, Wataru Ogawa, Masato Kasuga and Sankar Ghosh. 2009. The kinase PDK1 integrates Tcell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells .Nature Immunology, 10(2): 158-166. Feb 1, 2009
  11. Sung Gyoo Park, Hyun Mi Ryu, Seong-oe Lim, Yong-il Kim, Soon B. Hwang, and Guhung Jung. 2005. Interferon-g Inhibits Hepatitis B Virus-Induced NF-kB Activation through Nuclear Localization of NIK. Gastroenterology,128:2042-2053.
  12. Sung Gyoo Park, Guhung Jung. 2001. Human Hepatitis B Virus Polymerase Interacts with the Molecular Chaperonin Hsp60. Journal of Virology,75: 6962-6968.
관심연구분야