Education
B.S., Seoul National University (2009)
Ph. D., Seoul National University (2015)
Research Field
- Development of analytical platforms for understanding metabolic diseases.
- Development of therapeutic strategies for treatment of metabolic diseases.
Representative Publication
- Kang, Y. P., Mockabee-Macias, A., Jiang, C., Falzone,A., Prieto-Farigua, N., Stone E., Harris, I. S., and DeNicola, G. M.Non-canonical glutamate-cysteine ligaseactivity protects against ferroptosis. Cell Metabolism, 33, 1. 2021
- Kang, Y. P.,Falzone, A., Liu, M., González-Sánchez, P., Choi, B.-H., Coloff, J. L., Saller,J. J., Karreth, F. A., & DeNicola, G. M. PHGDH supports liver ceramidesynthesis and sustains lipid homeostasis. Cancer & Metabolism, 8, 6. 2020.
- Long,N. P., Nghi, T. D., Kang, Y. P., Anh, N. H., Kim, H. M., Park, S.K., & Kwon, S. W. Toward a Standardized Strategy of Clinical Metabolomicsfor the Advancement of Precision Medicine. Metabolites, 10, 51.2020.
- Ward, N. P., Kang, Y. P., Falzone, A., Boyle, T. A., & DeNicola, G. M. Nicotinamide NucleotideTranshydrogenase Regulates Mitochondrial Metabolism in NSCLC ThroughMaintenance of Fe-S Protein Function. Journal of Experimental Medicine e20191689. 2020.
- Kang, Y. P., Torrente, L., Falzone, A., Elkins, C. M., Liu, M., Asara, J.M.,Dibble, C.C. & DeNicola, G. M. Cysteine dioxygenase 1 is a metabolicliability for non-small cell lung cancer.Elife. e45572. 2019.
- Kang, Y. P., Yoon, J. H., Long, N. P., Koo, G.-B., Noh, H.-J., Oh, S.-J.,Lee, S. B., Kim, H. M., Hong, J. H., Lee, W. J., Lee, S. J., Hong, S.-S., Kwon,S. W., & Kim, Y.-D. Spheroid-induced Epithelial-Mesenchymal TransitionProvokes Global Alteration of Breast Cancer Lipidome: A Multi-Layered OmicsAnalysis. Frontiers in Oncology, 9, 145. 2019.
- Harris, I. S., Endress, J. E., Coloff, J. L., Selfors, L. M.,McBrayer, S. K., Rosenbluth, J. M., Takahashi, N., Dhakal, S., Koduri, V.,Oser, M. G., Schauer, M. J., Doherty, L, M., Hong, A. L., Kang, Y. P., Younger, S. T., Doench, J. G., Hahn, W. C.,Buhrlage, S. J., DeNicola, G. M., Kaelin Jr, W. G., Brugge, J. S.Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells uponGlutathione Depletion. Cell Metabolism, 29, 5, 1166-1181. 2019Doi: https://doi.org/10.1016/j.cmet.2019.01.020.
- Kang, Y. P., Ward, N. P. & DeNicola, G. M. Recent advances in cancermetabolism: a technological perspective. Experimental & molecular medicine, 50, 31. 2018. Review
