Research Field
1. Developing nanomedicine manufacturing technologies
2. Bio-drug delivery system of nucleic acid, cellbased therapeutics
3. Establishment of innovative vaccine formulation
4. Stimulus-guided delivery system
Representative Publication
- Gayong Shim, Su-Eun Han, Yong-Hee Yu, Sangbin Lee , Han Young Lee, Kwangmeyung Kim, Ick Chan Kwon, Tae Gwan Park, Young Bong Kim, Yong Seok Choi, Chan-Wha Kim, Yu-Kyoung Oh. Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drug. J. Control. Release 2011 (in press)
- Hee-Jeong Cho, Su-Eun Han, Saewon Im, Young Lee, Young Bong Kim, Taehoon Chun, Yu-Kyoung Oh. Maltosylated polyethylenimine-based triple nanocomplexes of human papillomavirus 16 L1 protein and DNA as a vaccine co-delivery system. Biomaterials 2011 (in press)
- Sang Myoung Noh, Su Eun Han, Gayong Shim, Kyoung Eun Lee, Chan-Wha Kim, Sung Sik Han, Yongseok Choi, Young Keun Kim, Won-Ki Kim, Yu-Kyoung Oh. Tocopheryl oligochitosan-based self assembling oligomersomes for siRNA delivery. Biomateirals 32, pp. 849-857 (2011)
- Eun-Joong Kim, Hee-Jeong Cho, Daeui Park, Ji Yeon Kim, Young Bong Kim, Tae Gwan Park, Chang-Koo Shim, Yu-Kyoung Oh. Anti-fibrotic effect of MMP13-encoding plasmid DNA delivered using polyethylenimine shielded with hyaluronic acid. Mol. Ther. 19, pp. 355-361 (2011)
- Sang Myoung Noh, Myung Ok Park, Gayong Shim, Su Eun Han, Han Young Lee, Jun Hyuk Huh, Myung Sook Kim, Sung Sik Bang, Kwangmeyung Kim, Ick Chan Kwon, Jin-Seok Kim, Kwang Hyun Baek, Yu-Kyoung Oh, Pegylated poly-l-arginine derivatives of chitosan for effective delivery of siRNA. J. Control. Release. 145, pp. 159-164 (2010)
- Rae Sung Chang, Jiyeon Kim, Han Young Lee, Su-Eun Han, Jinhee Na, Kwangmeyung Kim, Ick Chan Kwon, Young Bong Kim, Yu-Kyoung Oh, Reduced dose-limiting toxicity of intraperitoneal mitoxantrone chemotherapy using cardiolipin-based anionic liposomes. Nanomedicine 6, pp. 769-776 (2010)
- In-Young Kim, Young-Sook Kang, Doo Sung Lee, Heon-Joo Park, Eun-Kyung Choi, Yu-Kyoung Oh, Hye-Jung Son, Jin-Seok Kim. Antitumor activity of EGFR targeted pH-sensitive immunoliposomes encapsulating gemcitabine in A549 xenograft nude mice. J. Control. Rel. (2009)
- Min Sung Suh, Gayong Shim, Han Young Lee, Su-Eun Han, Yong-Hee Yu, Yongseok Choi, Kwangmeyung Kim, Ick Chan Kwon, Kwon Yeon Weon, Young Bong Kim, Yu-Kyoung Oh. Anionic amino acid-derived cationic lipid for siRNA delivery. J. Control. Rel. (2009)
- Eun-Joong Kim, Gayong Shim, Kwangmyeung Kim, Ick Chan Kwon, Yu-Kyoung Oh, Chang-Koo Shim. Hyaluronic acid complexed to biodegradable poly-L-arginine for targeted delivery of siRNAs. J. Gene Med. 11, pp. 791-803 (2009)
- Hyun-Ah Cho, In-Sung Park, Tae-Woo Kim, Yu-Kyoung Oh, Ki-Sook Yang, Jin-Seok Kim. Suppression of hepatitis B virus-derived human hepatocellular carcinoma by NIK-specific siRNA using liver-targeting liposomes. Arch. Pharm. Res. 32, pp. 1077-1086 (2009)
- Yu-Kyoung Oh, Tae Gwan Park. siRNA delivery systems for cancer treatment. Adv. Drug Del. Rev. 61(10), pp. 850-862 (2009)
- Hae Yun Nam, Seok Min Kwon, Hyunjin Chung, Seung-Young Lee, Seung-Hae Kwon, Hyesung Jeon, Yoonkyung Kim, Jae Hyung Park, Joon Kim, Songwook Her, Yu-Kyoung Oh, Ick Chan Kwon, Kwangmeyung Kim, Seo Young Jeong. Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles. J. Control. Rel. 135, pp. 259-267(2009)
- So Jin Lee, Kyeongsoon Park, Yu-Kyoung Oh, Seung-Hae Kwon c, Songwook Her, In-San Kim, Kuiwon Choi, Sung Jun Lee, Hoyoung Kim, Se Geun Lee, Kwangmeyung Kim, Ick Chan Kwon. Tumor specificity and therapeutic efficacy of photosensitizer-encapsulated glycol chitosan-based nanoparticles in tumor-bearing mice. Biomaterials 30, pp. 2929-2939 (2009)
- Jung Mogg Kim, Dong Ho Lee, Joo Sung Kim, Hong-Gyu Park, Yeong-Jeong Kim, Yu-Kyoung Oh, Hyun Chae Jung. 5,7-dihydroxy-3,4,6-trimethoxyflavone inhibits the inflammatory effects induced by Bacteroides fragilis enterotoxin via dissociating the complex of Hsp90 and IKK- in intestinal epithelial cell culture. Clin. Exp. Immunol. 155(3), pp. 541-542 (2009)
- Su-Eun Han, Hyungu Kang, Ga Yong Shim, Sun Jae Kim, Han-Gon Choi, Jiseok Kim, Sei Kwang Hahn, Yu-Kyoung Oh. Cationic derivatives of biocompatible hyaluronic acids for delivery of siRNA and antisense oligonucleotides. J. Drug Target. 17(2), pp. 123-132 (2009)
- Sang Hee Kim, Eun Joong Kim, Joon Hyuk Hou, Jung Mogg Kim, Hang-Gon Choi, Chang-Koo Shim, Yu-Kyoung Oh. Opsonized erythrocyte ghosts for liver-targeted delivery of antisense oligodeoxynucleotides. Biomaterials 30(5), pp. 959-967 (2009)
- Ji Hoon Jeong, Hyejung Mok, Yu-Kyoung Oh, Tae Gwan Park. siRNA Conjugate Delivery Systems. Bioconjug. Chem. 20(1), pp. 5-14 (2009)
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