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교수진

Jae-Young Lee Associate Professor

MajorBioengineering / Drug delivery system
Office 21-415
Contact 02-880- 9398(office) / 9348(lab)
Email lee.jy@snu.ac.kr
Education

2011. 3 – 2016. 8 : College of Pharmacy, Seoul National University / PhD (Pharmaceutics)

2006. 3 – 2011. 2 : College of Pharmacy, Seoul National University / BS

Academic career

2023. 9 – present: College of Pharmacy, Seoul National University / Associate Professor

2017. 3 – 2023. 8: College of Pharmacy, Chungnam National University / Assistant/Associate Professor

2016. 9 – 2017. 2: Research Institute of Pharmaceutical Sciences, Seoul National University / Senior Researcher

Research Field
  • Biomaterial-based nano-platforms for cancer drug delivery and imaging
  • Functional protein expression and evaluation for drug delivery and therapy applications
  • Formulation design and development
Representative Publication
  1. Tailoring Renal Clearable Zwitterionic Cyclodextrin for Colorectal Cancer-Selective Drug DeliveryNature Nanotechnology (2023) https://doi.org/10.1038/s41565-023-01381-8
  2. Enhancement of the therapeutic efficacy of the MAP regimen using thiamine pyrophosphate-decorated albumin nanoclusters in osteosarcoma treatmentBioengineering & Translational Medicine (2023) https://doi.org/10.1002/btm2.10472
  3. Hypoxia-alleviating hemoglobin nanoclusters for sensitizing chemo-photodynamic therapy of cervical cancerChemical Engineering Journal (2023) https://doi.org/10.1016/j.cej.2022.141224
  4. Bone tumor-homing nanotherapeutics for prolonged retention in tumor microenvironment and facilitated apoptotic process via mevalonate pathway inhibitionMaterials Today Bio (2023) https://doi.org/10.1016/j.mtbio.2023.100591
  5. Hydroxyapatite-binding albumin nanoclusters for enhancing bone tumor chemotherapy Journal of Controlled Release (2022) https://doi.org/10.1016/j.jconrel.2021.12.039
  6. PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responsesBiomaterials (2021) https://doi.org/10.1016/j.biomaterials.2021.120827
  7. Chondroitin sulfate-hybridized zein nanoparticles for tumor-targeted delivery of docetaxelCarbohydrate Polymers (2021) https://doi.org/10.1016/j.carbpol.2020.117187
  8. Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine stormNano Today (2021) https://doi.org/10.1016/j.nantod.2021.101149
  9. Blood component ridable and CD44 receptor targetable nanoparticles based on a maleimide-functionalized chondroitin sulfate derivativeCarbohydrate Polymers (2020) https://doi.org/10.1016/j.carbpol.2019.115568
  10. Curcumin-loaded lipid-hybridized cellulose nanofiber film ameliorates imiquimod-induced psoriasis-like dermatitis in miceBiomaterials (2018) https://doi.org/10.1016/j.biomaterials.2018.08.030
  11. Chemosensitizing indomethacin-conjugated chitosan oligosaccharide nanoparticles for tumor-targeted drug deliveryActa Biomaterialia (2017) https://doi.org/10.1016/j.actbio.2017.05.012
  12. Dual CD44 and folate receptor-targeted nanoparticles for cancer diagnosis and anticancer drug deliveryJournal of Controlled Release (2016) https://doi.org/10.1016/j.jconrel.2016.06.021
  13. Polyethylene glycol-conjugated chondroitin sulfate A derivative nanoparticles for tumor-targeted delivery of anticancer drugsCarbohydrate Polymers (2016) https://doi.org/10.1016/j.carbpol.2016.05.043
  14. Iodinated hyaluronic acid oligomer-based nanoassemblies for tumor-targeted drug delivery and cancer imagingBiomaterials (2016) https://doi.org/10.1016/j.biomaterials.2016.01.060
  15. Phenylboronic Acid-Decorated Chondroitin Sulfate A-Based Theranostic Nanoparticles for Enhanced Tumor Targeting and PenetrationAdvanced Functional Materials (2015) https://doi.org/10.1002/adfm.201500680