SKO Symposium Program
Date: November 18(Mon) ~ 19(Tue), 2024
Venue : The Chu Hall, College of Pharmacy, Seoul National University, Republic of Korea
Monday, November 18
15:30 ~ 16:00 Registration
16:00~16:20 Opening Ceremony
Opening Remarks: Prof. Dr. Keon Wook Kang (Dean, Seoul National University)
Congratulatory Address: Prof. Dr. Yasushi Ishihama (Kyoto University)
Session 1
Chair: Seungjin Lee (SNU), Nobuki Kazuta (KU)
16:20~16:35 Yong June Choi(Seoul National University)
Prevention of radiotherapy-induced pro-tumorigenic microenvironment by SFK inhibitors
16:35~16:50 Lei Zhang(Kyoto University)
Development of bisabolan-type meroterpenoids produced by Stachybotrys ruwenzoriensis RF-6853 as asparagine synthetase inhibitors
16:50~17:05 Jianyu Lin(Osaka University)
Biological property of marine natural product, fonsecinone D, as an inhibitor of extracellular vesicle production
17:05~17:20 Yun Seo Park(Seoul National University)
Cytotoxic peptaibols from Trichoderma strigosum
17:20~17:35 Aoi Taniguchi(Kyoto University)
Selective anticancer activities of low pH-responsive peptides and activity enhancement by anticancer drug conjugation
17:35~17:50 Reita Mashimo(Osaka University)
Design, synthesis and bioactivity evaluation of spliceostatin A derivatives for toxicity reduction
17:50~19:00 Welcome reception(Hoam Convention Center)
Thursday, November 19
Session 2
Chair: De Guzman Arvie Camille (SNU), Masaharu Takatsuki (OU)
09:00~09:15 Nguyen Pham Khanh Tien(Kyoto University)
Identification of meibomian gland testosterone metabolites produced by tissue-intrinsic intracrine deactivation activity
09:15~09:30 Seina Yarimizu(Osaka University)
Immobilization of biomolecule on silane functionalized graphene grid for Cryo-EM
09:30~09:45 Yun Jae Cha(Seoul National University)
Lipidomic Network in the Cortex and Hippocampus of the 5xFAD Mouse
09:45~10:00 Tsuyoshi Hirata(Kyoto University)
Cell-selective binding for targeted delivery of therapeutic cells by VHH antibody modification.
10:00~10:15 Miyu Mae(Osaka University)
Photocatalytic and highly-regioselective H/D exchange at α-thio C(sp3)-H bonds
10:15~10:30 Sihang Jo(Seoul National University)
Biosynthesis-encoded lipogenic acetyl-CoA measurement using NMR reveals glucose-driven lipogenesis and glutamine’s alternative roles in kidney cancer
10:30~10:45 Coffee break
Session 3
Chair: Chair: Jianyu LIN (OU), Taichi Yumura (KU)
10:45~11:00 Tomoki Yoshimura(Osaka University)
Development of pyranose-type novel artificial nucleic acid for oligonucleotide therapeutics
11:00~11:15 Yun A Yum(Seoul National University)
Design, synthesis, and biological evaluation of 5′,7-disubstituted-7-deaza-4′-thioadenosines as potent HASPIN kinase inhibitor
11:15~11:30 Asato Maeda(Kyoto University)
Enzymatic phospho-probing for detecting protein conformational changes on a proteome scale
11:30~11:45 Dong Jun Kim(Seoul National University)
Simple and efficient enantioselective α‑deuteration method of α‑amino acids without external chiral sources
11:45~12:00 Kazuma Kurokawa(Kyoto University)
Synthesis of novel graphene nanoribbons having non-benzenoid units
12:00~13:30 Lunch
Session 4
Chair: Seina Yarimizu (OU), Young Hoon Song (SNU)
13:30~13:45 Jaeyong Lee(Seoul National University)
Phase-transfer catalyzed enantioselective aza-Michael addition to enones: comprehensive study of synthetic utility and reaction mechanism
13:45~14:00 Daiki Hasegawa(Kyoto University)
Synthesis of azocine-fused indoles via gold(I)-catalysed cyclisation of azido-alkynes
14:00~14:15 Riko Sekiguchi(Osaka University)
Design, synthesis and optical characterization of polysubstituted isoindolo[2,1-a]quinoline derivatives for improvement of fluorescence quantum yield
14:15~14:30 Honghui Lee(Seoul National University)
Total synthesis of deinococcucin family: the discovery of novel anti-angiogenic derivatives from natural aminoglycolipid structures
14:30~14:45 Kentaro Nishiyama(Kyoto University)
Proximity-induced chemical reactions triggered by antibody-antigen interaction
14:45~15:00 Yutaro Ito(Osaka University)
Cross-dehydrogenative coupling reaction of p-aminophenols with naphthols catalyzed by a heterogeneous oxovanadium catalyst V-MPS4
15:00~15:15 La Minh Thanh(Seoul National University)
Discovery of Indazole-Based HSP90 C-Terminal Inhibitors for Targeting HER2-Positive Breast Cancer
15:15~15:30 Coffee break
Session 5
Chair: Kentaro Nishiyama (KU), Jaeyong Lee (SNU)
15:30~15:45 Taichi Yumura(Kyoto University)
Single electron reduction-initiated transformations of α,β-unsaturated carboxylic acids catalyzed by hybrid boronic acid
15:45~16:00 Masakatsu Takatsuki(Osaka University)
Development of a synthetic method for the synthesis of heterocycles with spirocyclobutanes: Intramolecular reaction of bicyclobutane with vinylethers using gold or acid catalysts
16:00~16:15 Le Bich Hang Pham(Seoul National University)
Development of Organelle Selective AIEgens for Cancer Cell Ablation
16:15~16:30 Nobuki Kazuta(Kyoto University)
Development of novel radioligands targeting prostate-specific membrane antigen for diagnosis and therapy of prostate cancer
16:30~16:45 Kazutoshi Ihara(Osaka University)
Development of product-selective Buchwald-Hartwig coupling reactions using continuous irradiation microwaves and metal nanoparticle catalysts; design, synthesis and functional evaluation of monoamine oxidase B (MAO-B) inhibitors
16:45~17:00 Seungchan An(Seoul National University)
Machine learning-based prediction of the phenotypic effect of flavonoids on adiponectin biosynthesis
17:00~17:15 Haruka Hoshi(Kyoto University)
Exploration of GPCR functions stably solubilized by a novel cocktail of phospholipid analogs
17:15~17:30 losing Remarks and Announcement of the next sumposium
Prof. Dr. Mitsuhiro Arisawa (Osaka University)
18:00 ~ Farewell Party (Meeting place is to be announced)
