SEOUL NATIONAL UNIVERSITY
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 Shin, Jongheon 사진
  • 성명 Shin, Jongheon
  • 직위 Professor (Ph.D., Univ. of California at San Diego)
  • 학과
  • 전공 Natural Products Science
  • 사무실 141-305
  • 홈페이지
  • 이메일 shinj@snu.ac.kr
  • 연락처 880-2484/880-2483

Education

Ph.D. University of California at San Diego

Research Field

1. Isolation, structure determination and development of marine natural products
2. Structure determination of bioactive compounds from diverse natural sources including microorganisms and herbal medicines
3. Simultaneous analysis of bioactive constituents from herbal medicines

Representative Publication

A. Ham. B. Kim, U. Koo, K.-W. Nam, S.-J. Lee, K. H. Kim, J. Shin, and W. Mar “Spirafolide from bay leaf (Laurus nobilis) prevents dopamine-induced apoptosis by decreasing reactive oxygen species production in human neuroblastoma SH-SY5Y cells” Arch. Pharm. Res. 33, pp. 1953-1958 (2010)

J.-e. Jeon, Z. Na, M. Jung, H.-S. Lee, C. J. Shim, K. Nahm, K.-B. Oh, and J. Shin “Discorhabdins from the Korean Marine Sponge Sceptrella sp.” J. Nat. Prod. 73, pp. 258-262 (2010)

K.-B. Oh, K.-W. Nam, H. Ahn, J. Shin, S. Kim, and W. Mar “Therapeutic effect of (Z)-3-(2,5-dimethoxyphenyl)-2-(4-methoxyphenyl) acrylonitrile (DMMA) against Staphylococcus aureus infection in a murine model” Biochem. Biophys. Res. Commun. 396, pp. 440-444 (2010)

T. H. Won, S. K. Ryu, S. S. Kang, and J. Shin “Simultaneous analysis of bioactive metabolites from Rehmannia glutinosa by HPLC-DAD-MS/MS” Nat. Prod. Sci 16, pp. 116-122 (2010)

E.-Y. Cho, S.-J. Lee, K.-W. Nam, J. Shin, K.-B. Oh, K. H. Kim, and W. Mar “Amelioration of oxygen and glucose deprivation-induced neuronal death by chloroform fraction of bay leaves (Laurus nobilis)” Biosci. Biotech. Biochem 74, pp. 2029-2035 (2010)

S.-C. Chung, T.-I. Kim, C.-H. Ahn, J. Shin, and K.-B. Oh “Candida albicans PHO81 is required for the inhibition of hyphal development by farnesoic acid” FEBS Lett. 584, pp. 4639-4645 (2010)

K.-B. Oh, H. B. Jeon, Y.-R. Han, Y.-J. Lee, J. Park, S.-H. Lee, D. Yang, M. Kwon, J. Shin, and H.-S. Lee “Bromophenols as Candida albicans isocitrate lyase inhibitors” Bioorg. Med. Chem. Lett. 20, pp. 6644-6648 (2010)

K. H. Jang, G. W. Kang, J.-e. Jeon, C. Lim, H.-S. Lee, C. J. Sim, K.-B. Oh, and J. Shin “Haliclonin A, a new macrocyclic diamide from the sponge Haliclona sp.” Org. Lett. 11, pp. 1713-1716 (2009)

H. S. Lee, K. M. Yoon, Y. R. Han, K. J. Lee, S. C. Chung, T. I. Kim, S. H. Lee, J. Shin, and K.-B. Oh "5-Hydroxyindole-type alkaloids, as Candida albicans isocitrate lyase inhibitors, from the tropical sponge Hyrtios sp." Bioorg. Med. Chem. Lett. 19, pp. 1051-1053 (2009)

J.-W. Ahn, K. H. Jang, S.-C. Chung, K.-B. Oh, and J. Shin “Sorangiadenosine, a new sesquiterpene adenoside from the myxobacterium Sorangium cellulosum” Org. Lett. 10, pp. 1167-1169 (2008)

J. Song, W. Jeong, N. Wang, H.-S. Lee, C. J. Shim, K.-B. Oh, and J. Shin “Scalarene sesterterpenes from the sponge Smenospongia sp.” J. Nat. Prod. 71, pp. 1866-1871 (2008)

M. Jung, K. H. Jang, B. Kim, B. H. Lee, B. W. Choi, K.-B. Oh, and J. Shin “Meroditerpenoids from the brown alga Sargassum siliquastrum” J. Nat. Prod. 71, pp. 1714-1719 (2008)

K. H. Jang, J.-e. Jeon, S. Ryu, H.-S. Lee, K.-B. Oh, and J. Shin “Polyoxygenated diterpenes from the sponge Phorbas sp.” J. Nat. Prod. 71, 1701-1707 (2008)

Y. H. Chang, D. Shin, Z. Na, H.-S. Lee, D.-D. Kim, K.-B. Oh, and J. Shin “Dihydroxystyrene metabolites from an association of the sponges Poecillastra wondoensis and Jaspis sp.” J. Nat. Prod. 71, pp. 779-783 (2008)

N. Wang, J. Song, K. H. Jang, H.-S. Lee, X. Li, K.-B. Oh, and J. Shin “Sesterterpenoids from the sponge Sarcotragus sp.” J. Nat. Prod. 71, pp. 551-557 (2008)

H. W. Chang, K. H. Jang, D. Lee, H. R. Kang, T.-Y. Kim, B. H. Lee, B. W. Choi, S. Kim, and J. Shin “Monoglycerides from the brown alga Sargassum sagamianum: Isolation, synthesis, and biological activity” Bioorg. Med. Chem. Lett. 18, pp. 3589-3592 (2008)

K. H. Jang, S.-C. Chung, J. Shin, S.-H. Lee, T.-I. Kim, H.-S. Lee, and K.-B. Oh, "Aaptamines as sortase A inhibitors from the tropical sponge Aaptos aaptos" Bioorg. Med. Chem. Lett. 17, pp. 5366-5369 (2007)

H.-S. Lee, T.-H. Lee, S. H. Yang, H. J. Shin, J. Shin, and K.-B. Oh, "Sesterterpene sulfates as isocitrate lyase inhibitors from tropical sponge Hippospongia sp." Bioorg. Med. Chem. Lett. 17, pp. 2483-2486 (2007)

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762-8322

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