- 성명 Jae-Young Lee
- 직위 Associate Professor
- 학과 Pharmacy
- 전공 Bioengineering / Drug delivery system
- 사무실 21-415
- 홈페이지 http://ywchin.snu.ac.kr
- 이메일 lee.jy@snu.ac.kr
- 연락처 +82-2-880- 9398(office) / 9348(lab)
Education
- 2011. 3 - 2016. 8: College of Pharmacy, Seoul National University / PhD (Pharmaceutics)
- 2006. 3 - 2011. 2: College of Pharmacy, Seoul National University / BS
Academic career
- 2023. 9 - present: College of Pharmacy, Seoul National University / Associate Professor
- 2017. 3 - 2023. 8: College of Pharmacy, Chungnam National University / Assistant/Associate Professor
- 2016. 9 - 2017. 2: Research Institute of Pharmaceutical Sciences, Seoul National University / Senior Researcher
Research Field
1. Biomaterial-based nano-platforms for cancer drug delivery and imaging
2. Functional protein expression and evaluation for drug delivery and therapy applications
3. Formulation design and development
Representative Publication
1. Tailoring Renal Clearable Zwitterionic Cyclodextrin for Colorectal Cancer-Selective Drug Delivery
Nature Nanotechnology (2023) https://doi.org/10.1038/s41565-023-01381-8
2. Enhancement of the therapeutic efficacy of the MAP regimen using thiamine pyrophosphate-decorated albumin nanoclusters in osteosarcoma treatment
Bioengineering & Translational Medicine (2023) https://doi.org/10.1002/btm2.10472
3. Hypoxia-alleviating hemoglobin nanoclusters for sensitizing chemo-photodynamic therapy of cervical cancer
Chemical Engineering Journal (2023) https://doi.org/10.1016/j.cej.2022.141224
4. Bone tumor-homing nanotherapeutics for prolonged retention in tumor microenvironment and facilitated apoptotic process via mevalonate pathway inhibition
Materials Today Bio (2023) https://doi.org/10.1016/j.mtbio.2023.100591
5. Hydroxyapatite-binding albumin nanoclusters for enhancing bone tumor chemotherapy
Journal of Controlled Release (2022) https://doi.org/10.1016/j.jconrel.2021.12.039
6. PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responses
Biomaterials (2021) https://doi.org/10.1016/j.biomaterials.2021.120827
7. Chondroitin sulfate-hybridized zein nanoparticles for tumor-targeted delivery of docetaxel
Carbohydrate Polymers (2021) https://doi.org/10.1016/j.carbpol.2020.117187
8. Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm
Nano Today (2021) https://doi.org/10.1016/j.nantod.2021.101149
9. Blood component ridable and CD44 receptor targetable nanoparticles based on a maleimide-functionalized chondroitin sulfate derivative
Carbohydrate Polymers (2020) https://doi.org/10.1016/j.carbpol.2019.115568
10. Curcumin-loaded lipid-hybridized cellulose nanofiber film ameliorates imiquimod-induced psoriasis-like dermatitis in mice
Biomaterials (2018) https://doi.org/10.1016/j.biomaterials.2018.08.030
11. Chemosensitizing indomethacin-conjugated chitosan oligosaccharide nanoparticles for tumor-targeted drug delivery
Acta Biomaterialia (2017) https://doi.org/10.1016/j.actbio.2017.05.012
12. Dual CD44 and folate receptor-targeted nanoparticles for cancer diagnosis and anticancer drug delivery
Journal of Controlled Release (2016) https://doi.org/10.1016/j.jconrel.2016.06.021
13. Polyethylene glycol-conjugated chondroitin sulfate A derivative nanoparticles for tumor-targeted delivery of anticancer drugs
Carbohydrate Polymers (2016) https://doi.org/10.1016/j.carbpol.2016.05.043
14. Iodinated hyaluronic acid oligomer-based nanoassemblies for tumor-targeted drug delivery and cancer imaging
Biomaterials (2016) https://doi.org/10.1016/j.biomaterials.2016.01.060
15. Phenylboronic Acid-Decorated Chondroitin Sulfate A-Based Theranostic Nanoparticles for Enhanced Tumor Targeting and Penetration
Advanced Functional Materials (2015) https://doi.org/10.1002/adfm.201500680