Research Institute of Pharmaceutical Sciences
Building #21-104, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu,
Seoul 151-742, Korea
Tel: +82-2-880-7827, Fax: +82-2-884-8334
The Institute was founded in the College March 24, 1981. To support the Institute and to promote research activities of the faculty members, the College established "The Foundation for Pharmaceutical Education and Research" by the funds donated from alumni as well as major domestic pharmaceutical industries. With the funds, the Foundation was legally incorporated into a non-profit organization, which was later approved by the University and the Ministry of Education on March 22, 1983. The Institute is the working institution of the Foundation ever since.
A brief history of the institute includes;
1981 Establishment of the Institute
1983 Establishment of the Foundation for Pharmaceutical Education and Research
1992 Completion of the Pharmaceutical Research Building
1997 Completion of the Pharmaceutical Animal Research Facility
1997 Promotion of the Institute to the Associate Research Institute of Seoul National University
1998 Designated as the Institute to the Associate Research Institute of the Korea Research Foundation
1998 Designated as the Advanced Material Support Research Institute by the Ministry of
2000 Completion of the Pharmaceutical Plant for Education and Research
2002 Renamed as the Seoul National University Research Institute of Pharmaceutical Science under the Seoul National University regime
The Institute consists of the Steering Committee, four Research Divisions, Central
Instruments Laboratory, Pharmaceutical Animal Facility and Pharmaceutical Plant for
Education and Research. The Steering Committee consists of seven members, i.e., Director, four Division heads, the Laboratory chief and a Faculty member. The four Research Divisions include Basic Pharmaceutical Science, Drug Development, Safety and Efficacy and Environmental Hygiene.
The research institute has most qualified researchers in the field. First of all, 43 faculties of the College of Pharmacy participate in the institute. Secondly, over 30 researchers with Ph.D.degree as well as over 250 graduate students take parts in the institute. Furthermore, 17supportive assistants are responsible for the maintenance and service for the institute to support various research activities in the institute.
Central Instruments Laboratory
Building #20,#21,#29, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu,
Seoul 151-742, Korea
The central Instruments laboratory was established in 1981, when the Research Institute of Pharmaceutical Science was first built, to maximize the utility of the instruments by centralizing expensive research equipment.
The Central Instruments Laboratory consists of the NMR Room, the Mass Spectroscope
Room, the IR Spectroscope Room, the Building #20 Instrument Laboratory, the Building #21 Instrument Laboratory and the Building #29 Instrument Laboratory.
The instruments for biological research are located at two places: the Building 29 Instrument Laboratory and the Building #20 Instrument Laboratory. Likewise, the instruments for chemical research are located at two places: the Building #21 Instrument Laboratory and the Building #20 Instrument Laboratory. Some essential chemical research equipment, such as the NMR, Mass Spectroscope, and IR Spectroscope, are located in separate rooms, in this case the NMR Room, the Mass Spectroscope Room and the IR Spectroscope Room, respectively. These rooms are located at the College of Pharmacy Building #21.
Currently, the central laboratory possesses more than 330 pieces of equipment, all of which are maintained and managed by six supportive technical assistants.
Animal Experimental Center
Building #141, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea
History and Objective
The center is established in December 1996 to support the researchers in carrying out animal experiments. The center keeps experimental animals, and is equipped with facilities like special cleaning and sterilization section and sophisticated instruments for conducting animal experiment, animal breeding and microbiological experiments. A support service team, consisting of one assistant and four animal feeders, is in charge of the maintenance of the facilities related to animal experiment. A group of professors, in charge of the animal experiments, and the steering committee of the institute, jointly examine and take decision on all relevant matters starting form legal regulations and ethical rules linked to animal experiments to expansion and improvement of facilities like installation of equipment and personnel recruitment. The Institutional Animal Care and Use Committee (IACUC) is responsible for reviewing all requests to use vertebrate animals, and ensuring compliance with federal regulations. The regulations for managing and using animals have been made based on the Guide for the Care and Use of Laboratory Animals (Institute of Laboratory Animal Resources, Commission on Life Sciences, National Research Council, USA).
The animal facility (1,071 m2), located in a separate building, was established to maintain research animals based on GLP guideline. To minimize the environmental contamination, animals are housed in a complete and semi-complete isolation in terms of air supply. The rooms in the building are categorized into three separate zones; the SPF animal zone for maintaining SPF animals with complete environmental isolation, a general animal zone for maintaining SPF animals with semi-complete environmental isolation and an office zone. Pathogen monitoring is routinely carried out for the SPF animal zone and the general animal zone. The general access to the facility is strictly limited while the access of the graduate students and researchers may be granted, provided that the individuals take an animal handling course and follow the current guideline of the animal facility.
Pharmaceutical Plant for Education and Research
Building #142, College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, Korea
Tel: +82-2-880-1346, Fax: +82-2-872-1795
History and objectives
The plant was founded on March 11, 2001 to produce highly competent individuals equipped with basic knowledge and its practical application in business. The plant has been designed to provide final year undergraduate students with practical training relevant to pharmaceutical plant, such as, practice in pharmacology, medicinal chemistry and pharmaceutical plant practice, thereby improving the quality of students in order to work in the 21st pharmaceutical industry. The academic program is devised to equip students with hand-on practical experience along with theoretical knowledge. Particular emphasis has been given in studying facts related to exploitation and production of new medicines.
The pharmaceutical plant (1,590 m2), located in a separate building, was established to facilitate the undergraduate education with pharmaceutical production and to provide facility for pilot scale production of test formulations. The facility was built according to the current KGMP guidelines and provides up-to-date production facilities for the production of solid dosage forms and parenteral formulations. The utilities (i.e., water and air) are separately supplied for solid dosage form production and parenteral formulation production to eliminate cross contamination.
The plant is in a five-story building. On the first floor, there are guard office, communication office, machine room and electricity room. The second floor is provided with facilities for conducting solid medicine manufacturing processes, such as, analysis of raw materials, mixing, drying, triangular positioning, capsule filling, coating, packaging etc. The third floor is called the injection floor as activities like raw material measurement, medicine preparation, filtration of injection, filling, sterilization and packaging are conducted thre. Professors' offices and laboratories are on the fourth floor while large lecture rooms and pharmaceutical service training institute are located in the fifth floor.