검색창 닫기

학술행사/세미나 안내 및 신청

The strategies to fight against acute and chronic viral infections
To establish the therapeutic strategies for viral infections, we have studied three approaches. First, we found novel anti-viral host cellular factor. Inhibition of kinesin family member KIF18A strongly suppressed influenza viral replication by preventing the nuclear export of viral ribonucleoprotein complexes. Second, we identified the underlying mechanism for T cell-mediated immunopathogenesis upon chronic viral infections. Sphingosine kinase 2 functions during chronic viral infection to limit T cell immune pathology, which subsequently aids in the establishment of virus-induced immunosuppression and the resultant viral persistence. Third, we identified novel candidate proteins that are associated with antigen presentation by dendritic cells, which potentially promotes the development of novel vaccines to prevent viral infections. Our results provide novel insights into the treatment of acute and chronic viral infections.


현재 페이지에 대한 의견이나 수정요청을 관리자에게 보내실 수 있습니다.
아래의 빈 칸에 내용을 간단히 작성해주세요.