SEOUL NATIONAL UNIVERSITY
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정석재사진

학  력

Ph.D., State University of New York at Buffalo

주요관심연구분야

1. Pharmacokinetic analysis를 이용한 약물의 disposition 특성에 관한 연구
2. Biopharmaceutics실험방법에 의한 흡수, 배설 및 대사 mechanism에 관한 연구
3. Disease state에서의 약물 pharmacokinetics의 변화에 관한 연구

대표논문자료

Kim MH, Maeng HJ, Yu KH, Lee KR, Takashi Tsuruo, Kim DD, Shim CK, Chung SJ, Evidence of carrier-mediated transport in the penetration of donepezil into the rat brain J Pharm Sci 99, pp. 1548-1566 (2010)

Yu KH, Lee YR, Ahn SH, Kim DD, Shim CK, Chung SJ, Contribution of a significant first-pass effect of dimethyl-4,4 '-dimethoxy-5,6,5 ',6'-dimethylene dioxybiphenyl-2,2 '-dicarboxylate in the liver to its poor bioavailability in rats. JOURNAL OF PHARMACY AND PHARMACOLOGY 61, pp. 1197-1203 (2009.09)

Yin YM, Cui FD, Kim JS, Choi MK, Choi BC, Chung SJ, Shim CK, Kim DD, Preparation, characterization and in vitro intestinal absorption of a dry emulsion formulation containing atorvastatin calcium. DRUG DELIVERY 16, pp. 30-36 (2009.11)

Jin HE, Hong SS, Choi MK, Maeng HJ, Kim DD, Chung SJ, Shim CK, Reduced antidiabetic effect of metformin and down-regulation of hepatic oct1 in rats with ethynylestradiol-induced cholestasis. PHARMACEUTICAL RESEARCH 26(3), pp. 549-559 (2009.11)

Yang R, Yang SG, Shim WS, Cui FD, Cheng G, Kim IW, Kim DD, Chung SJ, Shim CK, Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates. JOURNAL OF PHARMACEUTICAL SCIENCES 98(3), pp. 970-984 (2009.11)

Lee JH, Woo YA, Hwang IC, Kim CY, Kim DD, Shim CK, Chung SJ, Quantification of CKD-501, lobeglitazone, in rat plasma using a liquid-chromatography/tandem mass spectrometry method and its applications to pharmacokinetic studies. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 50, pp. 872-877 (2009.11)

Jin QR, Shim WS, Choi MK, Tian GY, Song IS, Yang SG, Kim DD, Chung SJ, Shim CK, Decreased urinary secretion of belotecan in folic acid-induced acute renal failure rats due to down-regulation of Oat1 and Bcrp. XENOBIOTICA 39, pp. 711-721 (2009.11)

Lee SH, Oh T, Jeon BY, Kwak EY, Shim WS, Cho SN, Kim DD, Chung SJ, Shim CK, Tissue-specific changes in mRNA expression of Abc and Slc transporters in murine pulmonary tuberculosis. XENOBIOTICA 39, pp. 738-748 (2009.11)

Shim WS, Park JH, Ahn SJ, Han L, Jin QR, Li H, Choi MK, Kim DD, Chung SJ, Shim CK, Testosterone-independent down-regulation of oct2 in the kidney medulla from a uranyl nitrate-induced rat model of acute renal failure: Effects on distribution of a model organic cation, tetraethylammonium. JOURNAL OF PHARMACEUTICAL SCIENCES 98, pp. 739-747 (2009.11)

Yin YM, Cui FD, Mu CF, Choi MK, Kim JS, Chung SJ, Shim CK, Kim DD, Docetaxel microemulsion for enhanced oral bioavailability: Preparation and in vitro and in vivo evaluation. JOURNAL OF CONTROLLED RELEASE 140, pp. 86-94 (2009.12)

Hwang, SM/Kim, DD/Chung, SJ/Shim, CK, Delivery of ofloxacin to the lung and alveolar macrophages via hyaluronan microspheres for the treatment of tuberculosis. JOURNAL OF CONTROLLED RELEASE 129, pp. 100-106 (2008.07)

Shim WS, Park JH, Ahn SJ, Han L, Jin QR, Li H, Choi MK, Kim DD, Chung SJ, Shim CK, Testosterone-independent down-regulation of Oct2 in the kidney medulla from a uranyl nitrate-induced rat model of acute renal failure: Effects on distribution of a model organic cation, tetraethylammonium. JOURNAL OF PHARMACEUTICAL SCIENCES, (2008.05)

Li, H/Jin, HE/Kim, W/Han, YH/Kim, DD/Chung, SJ/Shim, CK, Involvement of P-glycoprotein, multidrug resistance protein 2 and breast cancer resistance protein in the transport of belotecan and topotecan in Caco-2 and MDCKII cells. PHARMACEUTICAL RESEARCH 25, pp. 2601-2612 (2008.01)

Yang R, Yang SG, Shim WS, Cui F, Cheng G, Kim IW, Kim DD, Chung SJ, Shim CK, Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates. JOURNAL OF PHARMACEUTICAL SCIENCES, (2008.01)

Jin HE, Hong SS, Choi MK, Maeng HJ, Kim DD, Chung SJ, Shim CK, Reduced antidiabetic effect of metformin and down-regulation of hepatic OCT1 in rats with ethynylestridiol-induced cholestasis. PHARMACEUTICAL RESEARCH, (2008.01)
 

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